近年来,铝塑药品泡罩包装在我国得到了迅速发展。由于储存时间长、携带方便等特点,这种包装越来越受到制药公司和消费者的欢迎,并逐渐取代传统玻璃瓶。包装和散装包装已成为固体药品包装的主流。
Aluminum-plastic blister packaging, also known as blister packaging, is a new type of solid medicine packaging. First, the transparent plastic hard sheet is blister-molded, and solid medicines such as tablets, pills, capsules, etc. are filled in the groove, and then heated and bonded with the adhesive-coated aluminum foil to form an independent sealed package.
At present, many domestic solid medicines are still packaged in glass bottles. Although they can avoid light, moisture, and oxidation, they have large packaging capacity and low technological content. For high-demand specialty drugs, this traditional packaging form cannot effectively prevent deliquescence and mildew. This is also an important reason why large-volume brown glass bottle packaging is rapidly delisting in recent years. Compared with bottled medicines, the biggest advantage of blister packaging is that it is easy to carry and can reduce the pollution caused by the carrying and taking of medicines. Moreover, the blister packaging has gas barrier properties, moisture permeability, hygienic safety, production efficiency, and accurate dosage. It also has obvious advantages in terms of sex and extending the shelf life of drugs.
吸塑包装具有良好的阻隔性能是由于其原材料选用铝箔和塑料刚性片材。铝盒具有高密度的金属晶体结构,具有良好的阻挡性能和遮光性能;塑料刚性板必须具有足够的抗氧、二氧化碳和水蒸气的屏障性能,具有高透明度和不易开裂的机械强度。目前,最常用的医用吸塑包装材料是PVC片材和PVDC(聚偏二氯乙烯)。
PVC具有相容性好、易成型和密封、价格低、透明、阻隔性能和机械强度基本能满足医药包装的要求,但其阻挡水蒸气的能力和热稳定性较差,对防潮性要求较高。对于药品来说,PVC并不令人满意。
PVDC has high molecular density, high crystallinity and transparency, and good weather resistance. PVDC film is a kind of film with current barrier properties. The barrier property of PVDC film with the same thickness to oxygen is 1500 times that of PE and 100 times that of PP and PET. Moreover, its barrier performance to water vapor is also higher than that of PVC, making it an ideal material for blister packaging. Multi-layer composite hard sheet made of PVDC and other film materials composite or coating, such as PVC/PVIX, BOPP/PVDC, PVC/PVDC/PE, PVDC/OPP/PE, etc., oxygen permeability, moisture permeability and moisture resistance The performance and barrier properties are significantly higher than that of a single material film.
Another blister packaging material is vacuum aluminized film, which is a kind of film that deposits aluminum vapor on the base film in a high vacuum state. Currently, PET, CPP, PVC, OPP, PE, etc. are widely used. As the base film of vacuum aluminized film, in addition to the characteristics of the original base film, the aluminized film also has beautiful decoration and better barrier properties. The light transmittance, oxygen transmission rate and moisture transmission rate are only the original base. A few tenths or even one percent of the film is also one of the key development directions for blister packaging materials in the future.
吸塑包装的另一个优点是全自动的包装过程,最大程度的保证了药品包装的安全性。全自动吸塑包装机包括吸塑成型、药品灌装、封口、外包装纸箱成型、手工折叠插入、吸塑板进入、纸箱封箱,所有工序一次完成,健康安全。先进机型除了自动化程度高外,还配备了多个安全检测装置,包括包装盒和说明书的识别和检测,可大大提高安全性和卫生,并可有效减少药品误装。